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Pathology

Denise Schwahn, PhD, DVM, DACVP, leads the Division of Pathology, which provides support to Yerkes researchers and the larger Emory community as well as external investigators and collaborators. The Pathology faculty contributes to colony health surveillance by providing diagnostic support to the Animal Resources Division. As part of its mission, the Division of Pathology promotes an open exchange of ideas, interdepartmental and interdisciplinary collaborations, the establishment and refinement of animal models of human disease and the support of projects from external collaborators in need of nonhuman primate (NHP) experimentation. The Yerkes pathologists and technical staff provide investigators assistance in protocol development, disease diagnosis and specimen collections. In addition, Pathology faculty is actively involved in training residents, veterinary students, veterinary pathologists and research scientists in the field of NHP pathology. The Pathology Division participates in virtually all of the education and training programs the Yerkes Research Center and Emory University School of Medicine offer.

Yerkes-based pathologists conduct research focused on infectious diseases, including AIDS pathology, immunotherapy in the context of HIV infection, tuberculosis (TB), rectal microbicides, Babesia microti infection and pathogenesis, XMRV infection, malaria and Listeria monocytogenes.

Service Units

The Pathology Division encompasses all aspects of diagnostic pathology and is composed of these major units: Anatomic Pathology (includes the Necropsy/Gross Pathology and Histopathology/Electron Microscopy Laboratories), Clinical Pathology, Molecular Pathology, Biological Material Procurement and Biological Material Shipping. 

   Necropsy/Gross Pathology

This unit provides basic pathology support services including routine (diagnostic) necropsies for colony animals and the much more extensive experimental necropsies for numerous research protocols.  The routine necropsies consist of complete gross examinations and histological examination.

   Histopathology/Electron Microscopy Laboratory

This lab provides histopathology and electron microscopy services for Yerkes, all laboratory animals the Emory School of Medicine maintains, other Emory investigators as well as investigators from other institutions, including Morehouse College and the Mannheimer Foundation. Services include tissue processing, paraffin blocks processing and embedding, slide preparation, coverslipping, routine and special staining, electron microscopy and other to fulfill the requests of investigators. Dr. Sanjeev Gumber is the lab director.

   Clinical Pathology Laboratory

This lab provides reliable, timely, accurate and cost-effective services for clinical and experimental support to the Yerkes Research Center as well as Emory investigators and researchers at other institutions across the United States. Services include hematology, parasitology, microbiology, flow cytometry, Urinalysis, routine and specialized clinical chemistry, and coagulation profiles

   Molecular Pathology Core

The Molecular Pathology Core provides research and diagnostic support to researchers and veterinary pathologists at Yerkes, Emory and other institutions across the United States. Services include immunohistochemistry and in situ hybridization assays for various nonhuman primate pathogens, including viruses and bacteria, and cell markers. Core staff members also help researchers design research protocols to incorporate these molecular pathology techniques. Dr. Sanjeev Gumber is the core director.

   Biological Material Procurement

This Yerkes service is an important resource to investigators worldwide because of the biological specimens we collect and distribute for scientific research purposes. Samples can be collected and prepared according to the investigators’ needs. For more information about this resource, please contact yerkes-resources@rmy.emory.edu.

   Biological Material Shipping

Yerkes provides biological material shipping services for the Center and its investigators, including shipment of clinical samples and hazardous (infectious) samples by IATA-certified research technicians. For more information about this resource, please contact wyneikeree.y.igbinoba@emory.edu.

Division Faculty