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Scientific Service Cores

The Yerkes Research Center is home to six service cores, which help make the Center a specialized facility that serves as a resource to researchers worldwide. From offering state-of-the-art genetic information production and analysis to housing world-class imaging technology, our Center's researchers and Service Cores are available to help you with your research proposals and protocols.  

Biomarkers Core

With more than 40 years of experience providing hormone assays for Yerkes and Emory researchers as well as research colleagues nationwide, the Yerkes Biomarkers Core offers a range of technologies, including liquid chromatography with tandem mass spectrometry, ELISA, automated enzyme immunoassays and chemiluminescent immunoassays to quantify hormones in a variety of biomatrices. The laboratory currently provides determinations for more than 120 compounds validated for nonhuman primates, humans and some other mammalian species. For more information, contact Dr. Kelly Ethun.

Comparative AIDS Core

The Comparative AIDS Core is a vital component of the expanding Yerkes research programs in AIDS-related studies. The Core is designed to provide oversight and coordination for these studies, as well as the necessary technical, laboratory and animal research support. Currently, the Core includes all the non-investigator assigned sooty mangabeys, as well as a large number of rhesus macaques. During the past five years, the Core has provided approx. 2,000 nonhuman primate samples to Yerkes Core and Affiliate scientists. For more information, contact Dr. Joyce Cohen or Dr. Guido Silvestri.

Nonhuman Primate Genomics Core

The Yerkes National Primate Research Center Nonhuman Primate Genomics Core (GenCore) is a service laboratory that provides researchers at Yerkes, the Emory Vaccine Center (EVC) and the greater Emory community with access to cutting-edge, high-throughput genomic technologies, including Next Generation sequencing (NGS) and Microarray gene expression analysis. The GenCore, which features an Illumina HiSeq1000 System, an Affymetrix GeneChip platform and an Agilent Bioanalyzer, offers a diverse set of genomic assays, including NGS applications such as RNAseq, targeted resequencing, ChIP-seq and miRNA sequencing. The GenCore provides a start-to-finish solution, assisting in pre-experimental consultation, assay design, sample preparation, nucleic acid quality assessment and bioinformatics analysis. For more information, contact Dr. Steve Bosinger

Tetramer Core

The National Institutes of Health (NIH) Tetramer Core Facility, established in 1999 at the Yerkes Research Center, provides custom synthesis and distribution of soluble MHC-peptide tetramer reagents that can be used to stain antigen-specific T cells. In addition to Class I MHC tetramer production, the NIH Tetramer Facility also provides human and mouse CD1d tetramers and custom class II MHC reagents for four distinct HLA-DR alleles. For more information, contact Dr. John Altman.

Virology Core

The Yerkes Virology Core is a service laboratory providing necessary support for the management of the Yerkes macaque and mangabey colonies, through the use of serological and molecular testing for viruses. This management aspect includes the maintenance of the specific pathogen-free (SPF) rhesus macaque colony. Additionally, the Virology Core provides support for experimental studies ongoing at the Yerkes Research Center, Emory University, as well as outside the University.  The functions of the Virology Core also include the management of the BSL3 facilities at the Yerkes Research Center and the management of the radiation facilities. For more information, contact Dr. Thomas Vanderford.

Yerkes Imaging Core

The Yerkes Imaging Core offers state-of-the-art imaging capabilities for non-invasive studies of the anatomy, physiology and function of nonhuman primate and rodent brains. The Yerkes Imaging Core provides technology allowing researchers to see cell damage in a living brain, to make earlier diagnoses and to better answer questions surrounding the studies of neurophysiology, neuroscience, neurology and neurodegenerative diseases.

In addition to offering MRI and PET scanning capabilities, the Yerkes Imaging Core, housed in the Yerkes Neuroscience Facility, offers electronic and mechanical workshops, premier computation resources, in-house animal facilities and veterinary support during imaging studies. For more information, contact Dr. Phillip Zhe Sun.