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Transgenics is the branch of science that studies the effects of modifying an organism’s genome by adding genes that originate in different species. These genetically modified animals provide great insight to the functions of certain genes.

Yerkes researchers have developed a transgenic monkey model of Huntington’s disease (HD) in an effort better understand the underlying biology of HD, which may lead to the development of potential therapies.

Researchers at Yerkes have also successfully generated the first transgenic prairie voles, an important step toward unlocking the genetic secrets of pair bonding. The future application of this technology will enable scientists to perform a host of genetic manipulations that will help identify the brain mechanisms of social bonding and other complex social behaviors. This advancement may also have important implications for understanding and treating psychiatric disorders associated with impairments in social behavior.

Yerkes Investigators Studying Transgenics