Researcher and Pathologist
Yerkes National Primate Research Center
Lab Web Site:
Prachi Sharma, BVSc, AH, PhD, received her doctorate from the University of Georgia and trained at the Wisconsin National Primate Research Center before joining the Yerkes Research Center.
Dr. Sharma’s research is focused on the pathogenesis of simian immunodeficiency virus (SIV) in rhesus macaques and gastric tumors in sooty mangabeys, a natural host of SIV. This project is aimed primarily at elucidating specific interactions of lentivirus infection in mucosal compartments, identifying pathways of viral transmission and prevention as well as determining the role of mucosal compartments in the archiving of viral isolates over time.
In addition, Dr. Sharma is collaborating with Yerkes Pathology Division Chief Francois Villinger, DVM, PhD, to study the capacity of the human gamma-retrovirus XMRV to replicate and disseminate in rhesus macaques.
Aside from her research interests and duties as a pathologist, Dr. Sharma has set up a Molecular Pathology lab in the Division of Pathology at Yerkes. The lab performs immunohistochemistries, ISH and FISH for identifying various pathogens, such as SIV, helicobacter, CMV and XMRV in tissue sections.
View publications on PubMed