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Anthony Chan, DVM, PhD

Yerkes Researcher

Phone: 404-727-8347

Fax: 404-727-5289

Email: awchan@emory.edu

Lab Web Site:

Biography

Anthony W.S. Chan, DVM, PhD, studies nonhuman primate models of human inherited diseases, including developing transgenic reporter cells for noninvasive magnetic resonance imaging (MRI) and developing personal stem cells for cell therapy. In 2001, Dr. Chan created the first transgenic monkey, and in 2008, he created the first transgenic monkey model of human inherited disease, Huntington’s disease (HD). This animal model is expected to lead to greater understanding of the underlying biology of HD and to the development of potential therapies. In addition, this pioneering work is leading the way toward the development of nonhuman primate models of other genetic diseases.

He received his doctorate in veterinary medicine from the National Taiwan University in Taiwan, Republic of China. He later attended the University of Wisconsin-Madison and trained in the fields of endocrinology and reproductive physiology.

Dr. Chan was a guest speaker at the 2015 World Stem Cell Summit. He discussed his work to successfully create a nonhuman primate model of HD as a preclinical animal model for regenerative medicine. He also discussed his research focused on neural cells derived from induced pluripotent stem cells of the HD monkey model to be used in cell replacement therapy. This is an exciting new area of research that holds hope for developing and evaluating novel treatments, such as cell replacement therapy for HD. 

Dr. Chan is the director of a new NIH-funded resource based at the Yerkes National Primate Research Center, the Transgenic Huntington’s Disease Monkey Resource (THDMR). The mission of the THDMR is to facilitate basic and preclinical applications of the transgenic Huntington’s disease (HD) monkey model to advance scientific knowledge and the discovery of a cure for HD. More information is available here.

Publications

View publications on PubMed