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Guido Silvestri, MD

Division Chief
Microbiology and Immunology

Georgia Research Alliance Eminent Scholar in Comparative Pathology

Professor of Pathology and Laboratory Medicine
Emory University School of Medicine

Phone: 404-727-9139



Guido Silvestri, MD, is Chief of the Division of Microbiology & Immunology at the Yerkes National Primate Research Center. In addition, he is a Georgia Research Alliance Eminent Scholar in Comparative Pathology as well as Professor and Vice-Chair for Research in the Department of Pathology and Laboratory Medicine at the Emory University School of Medicine.

Since 1993, Dr. Silvestri has been involved in studies of AIDS pathogenesis, prevention and therapy, mostly using nonhuman primate models of SIV and SHIV infection, with particular focus on comparative studies of pathogenic and non-pathogenic primate lentiviral infections. Dr. Silvestri is currently the principal investigator of several NIH grants, including an R37 MERIT award, and he is involved in both the Consortium for AIDS Vaccine Studies in nonhuman primates and the Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (CHAVI-ID). He also receives funding from the Bill & Melinda Gates Foundation and the Foundation for AIDS Research (amfAR). He has authored or co-authored 187 peer-reviewed publications in this field, including some in the highest impact journals (Cell, Science, Nature, Nature Medicine, etc.). His work has been quoted more than 12,000 times and has been presented in plenary sessions at all the major HIV/AIDS conferences, such as the Conference on Retroviruses and Opportunities (CROI), the International AIDS Society and Keystone Symposia.

Dr. Silvestri is an Editor of the Journal of Virology, an Associate Editor of PLoS Pathogens and a past Editor of the Journal of Immunology. He also serves on the Editorial Boards of the Journal of Infectious Diseases and Clinical Microbiology Reviews.

He has served as Chairman or Standing Member in several study sections at the National Institutes of Health, Canadian Institutes of Health Research, France’s National Agency for AIDS Research (ANRS), amfAR and the European Commission. He is a member of the Scientific Committee of CROI and the International AIDS Society Scientific Working Group on HIV Cure. He was a Co-Chair of the 6th International AIDS Conference in Rome in July 2011.

In 2015, the Yerkes National Primate Research Center established a translational research program called ERASE AIDS (Emory Research Alliance to Stop/Eradicate AIDS). This new program builds on the existing expertise and scientific resources on the Emory campus to conduct transformative studies aimed at finding a cure for HIV infection. The program is based at Yerkes and has been established as a collaboration among Yerkes, the Emory University School of Medicine, the Emory Center for AIDS Research (CFAR) and the Office of the Provost. Dr. Silvestri directs ERASE AIDS, and a number of highly recognized scientists, including Dr. Raymond Schinazi, the inventor of some of the most widely used anti-HIV drugs, Dr. R. Paul Johnson, Yerkes Director, Dr. Rama Rao Amara, Dr. Ann Chahroudi, Dr. Eric Hunter and Dr. Mirko Paiardini, are collaborating on this new program. ERASE AIDS scientists are the recipients of more than ten individual and multi-center research grants that focus on curing HIV infection. These grants are supported by the NIH, the Bill & Melinda Gates Foundation and the American Foundation for AIDS Research (amfAR), thus representing one of the most productive and creative scientific communities in this highly competitive field of research.

This program is currently recruiting for an Associate or Assistant Professor. More information is available here.

For more information about Dr. Silvestri and his research, visit these sites:


View publications on PubMed